Guile See also Deceit, Deceive, Deception In the scriptures, guile is deceitful cunning. Blessed is the man in whose spirit there is no guile, Ps. 32:2 (Ps. 34:13; 1 Pet. 2:1). Nathanael was an Israelite in whom there was no guile, John 1:47 (D&C 41:9–11). Pure knowledge enlarges the soul without guile, D&C 121:42.