Issuethy issue, which thou begettest, Gen. 48:6.be cleansed from the issue of her blood, Lev. 12:7.any man hath a running issue … he is unclean, Lev. 15:2.heart … for out of it are the issues of life, Prov. 4:23.woman … diseased with an issue of blood twelve years, Matt. 9:20 (Mark 5:25; Luke 8:43).out of their mouths issued fire and smoke, Rev. 9:17.