Edward Dube was born in Chiramanzu, Zimbabwe, on May 12, 1962. He married Naume Keresia Salizani on December 9, 1989. They are the parents of four children.
He received a diploma in education in 1992 from Zimbabwe D.E. College and studied entrepreneurship at the University of South Africa in 2003.
He has served in several Church callings, including full-time missionary in Zimbabwe, district president, branch president, stake president, president of the Zimbabwe Harare Mission, and Area Seventy.